Protein name:
Thrombomodulin (TM) ;
Alternative:
CD:
CD141 ;
Organism:
Dog (Canis familiarisCanis lupus familiaris).
General Annotation
Function:
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MLRVLLLGVL | APAGLGLPTP | AQPQPRSSQC | MEHDCFQLFR | GPATFLAASQ |
100:
TCEGLGGHLM | TVRSSVAADV | ISLLLSGDGG | DGPRLWIGLQ | LRRGCSDPGQ |
150:
GGPLRGFQWV | TGDNRTSYSR | WARPHVGPAG | PPCAPLCVAV | SDAAAPAPGE |
200:
PAWEEQRCAA | EADGFLCEFH | FAASCRPLLV | DARAAAAAGV | SVTYSTPFGA |
250:
RGADFQALPA | GSSAAVAPFG | VQLACAAPRG | EAEARWGREA | PGAWDCSVEN |
300:
GGCQRACSAS | AGAPRCLCPA | DTYLQADGRS | CATFAEHSCH | KLCEHFCIPN |
350:
ASVPGSYLCM | CETGYQLAAD | QHRCEDVDDC | IQVPSLCPQL | CVNTRGAFEC |
400:
HCYPGYELVD | NECVEPVDPC | FGSKCEYQCQ | PVSQTDYRCI | CAEGFAPVPH |
450:
DPHRCQMFCN | QTACPADCDP | NSPTSCQCPE | GYILDDGFMC | TDIDECENGE |
500:
CPEACRNLPG | TYECICGPDS | PLAGQVATDC | GRIISDPDGD | SDSGSGEPPV |
550:
TPTPGVTPSP | SPVGPVHSGV | LIGISIASLS | LVVALLALLC | HLRKKQGAPR |
578:
AELEYKCGAP | AKEVVLQHVR | TEQMPQKL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Dog
Bovine
Human
Rat
Polyclonal Antibody for Dog TM
Polyclonal Antibody for Dog TM
Polyclonal Antibody for Dog TM
Polyclonal Antibody for Dog TM
Polyclonal Antibody for Dog TM
Monoclonal Antibody for Dog TM
Monoclonal Antibody for Dog TM
Monoclonal Antibody for Dog TM
Monoclonal Antibody for Dog TM
Monoclonal Antibody for Dog TM
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY